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This newsletter is supported through unrestricted funding provided by Genzyme Corporation.

Welcome to Nephrology Now, a monthly list of the most pertinent and/or potentionally controversial articles in clinical Nephrology. These articles are selected from a wide range of journals from throughout the Nephrology and Internal Medicine literature. We also include a selection of review articles, opinion pieces and cases that may be of interest.

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Original Research - General Nephrology

Bretzel RG et al.
Once-daily basal insulin glargine versus thrice-daily prandial insulin lispro in people with type 2 diabetes on oral hypoglycaemic agents (APOLLO): an open randomised controlled trial.
Lancet. 2008 Mar 29;371(9618):1073-84. [Free Abstract] [Full Text]

González E et al.
Early steroid treatment improves the recovery of renal function in patients with drug-induced acute interstitial nephritis.
Kidney Int. 2008 Apr;73(8):940-6. [Free Abstract] [Full Text]

Hu W et al.
Mycophenolate mofetil versus cyclophosphamide for inducing remission of ANCA vasculitis with moderate renal involvement.
Nephrol Dial Transplant. 2008 Apr;23(4):1307-12. [Free Abstract] [Full Text]

Karamanidou C et al.
A systematic review of the prevalence and determinants of nonadherence to phosphate binding medication in patients with end-stage renal disease.
BMC Nephrol. 2008 Jan 31;9:2. [Free Full Text]

Keuter XH et al.
A randomized multicenter study of the outcome of brachial-basilic arteriovenous fistula and prosthetic brachial-antecubital forearm loop as vascular access for hemodialysis.
J Vasc Surg. 2008 Feb;47(2):395-40. [Free Abstract] [Full Text]

Khurana A et al .
The effect of oral sodium phosphate drug products on renal function in adults undergoing bowel endoscopy.
Arch Intern Med. 2008 Mar 24;168(6):593-7. [Free Full Text]

Roy HK, Bianchi LK.
Purging the colon while preserving the kidneys.
Arch Intern Med. 2008 Mar 24;168(6):565-7. [Free Extract] [Full Text]

Selgas R et al.
No apparent survival disadvantage of high peritoneal membrane transport status after transfer to hemodialysis.
Nat Clin Pract Nephrol. 2008 Apr;4(4):188-9. [Free Abstract] [Full Text]

Strippoli GF et al.
Effects of statins in patients with chronic kidney disease: meta-analysis and meta-regression of randomised controlled trials.
BMJ. 2008 Mar 22;336(7645):645-51. [Free Full Text]

Tolwani AJ et al.
Standard versus High-Dose CVVHDF for ICU-Related Acute Renal Failure.
J Am Soc Nephrol. 2008 Mar 12; Epub ahead of print. [Free Abstract] [Full Text]

Tonelli M et al.
Ultrasound monitoring to detect access stenosis in hemodialysis patients: a systematic review.
Am J Kidney Dis. 2008 Apr;51(4):630-40. [Free Abstract] [Full Text]

Tzanakis IP et al .
Magnesium carbonate for phosphate control in patients on hemodialysis. A randomized controlled trial.
Int Urol Nephrol. 2008;40(1):193-201. [Free Full Text]

Systematic review validates the RIFLE criteria in acute kidney injury.
Nature Clinical Practice Nephrology (2008) 4, 178. [Free Abstract]


The ONTARGET Investigators.
Telmisartan, Ramipril, or Both in Patients at High Risk for Vascular Events.
N Engl J Med. 2008 Mar 31; [Free Full Text]

McMurray JJ et al.
ACE Inhibitors in Cardiovascular Disease -- Unbeatable?
N Engl J Med. 2008 Mar 31; [Free Full Commentary]


Kastelein JJ et al .
Simvastatin with or without ezetimibe in familial hypercholesterolemia.
N Engl J Med. 2008 Apr 3;358(14):1431-43. [Free Full Text]

Brown BG, Taylor AJ.
Does ENHANCE diminish confidence in lowering LDL or in ezetimibe?
N Engl J Med. 2008 Apr 3;358(14):1504-7. [Free Full Commentary]

Drazen JM et al .
Cholesterol lowering and ezetimibe.
N Engl J Med. 2008 Apr 3;358(14):1507-8. [Free Full Commentary]

Original Research - Transplantation

Aliabadi AZ et al.
Development of proteinuria after switch to sirolimus-based immunosuppression in long-term cardiac transplant patients.
Am J Transplant. 2008 Apr;8(4):854-61. [Free Full Text]
Full text access provided by Blackwell Synergy .

Aquino-Dias EC et al.
Non-invasive diagnosis of acute rejection in kidney transplants with delayed graft function.
Kidney Int. 2008 Apr;73(7):877-84. [Free Abstract] [Full Text]

Chandraker A, Mannon RB.
Care of the kidney transplant recipient.
Clin J Am Soc Nephrol. 2008 Mar;3 Suppl 2:S27-8. [Full Text]

Ciancio G et al.
A randomized trial of thymoglobulin vs. alemtuzumab (with lower dose maintenance immunosuppression) vs. daclizumab in renal transplantation at 24 months of follow-up.
Clin Transplant. 2008 Mar-Apr;22(2):200-10. [Free Abstract] [Full Text]

Opelz G et al.
Influence of Time of Rejection on Long-Term Graft Survival in Renal Transplantation.
Transplantation. 2008 Mar 15;85(5):661-666. [Free Abstract] [Full Text]

Reviews

Choudhury D, Luna-Salazar C; Medscape.
Preventive health care in chronic kidney disease and end-stage renal disease.
Nat Clin Pract Nephrol. 2008 Apr;4(4):194-206. [Free Full Text]

Maya ID, Allon M.
Vascular access: core curriculum 2008.
Am J Kidney Dis. 2008 Apr;51(4):702-8. [Free Full Text]

Kidney Disease: Improving Global Outcomes. KDIGO clinical practice guidelines for the prevention, diagnosis, evaluation, and treatment of Hepatitis C in chronic kidney disease.
Kidney International 2008; 73 (Suppl 109): S1-S99. [Free Outline]

Cases

Boseman P, Lewin M, Dillon J, Sethi S.
Marfan syndrome, MPGN, and bacterial endocarditis.
Am J Kidney Dis. 2008 Apr;51(4):697-701. [Free Full Text]

Zar T, Aglieco F, Ranga KV.
Quiz page April 2008: deafness, preauricular pits, and renal failure. BOR syndrome or Melnick-Fraser syndrome.
Am J Kidney Dis. 2008 Apr;51(4):A44-6. [Free Full Text]

Images

Mason WJ, Nickols HH .
Images in clinical medicine. Crystalluria from acyclovir use.
N Engl J Med. 2008 Mar 27;358(13):e14. [Free Full Text]

Stratta P, Barbe MC.
Images in clinical medicine. Green urine.
N Engl J Med. 2008 Mar 13;358(11):e12. [Free Full Text]

Conference Alert

7th Annual Conference on Prevention in Renal Disease.
Taking place in Toronto on September 19-20, 2008. For program details, faculty and on-line registration please visit www.nephroprevention.com

Educational Program

DAFOH is an educational organization of physicians worldwide which seeks to educate doctors and the general public about illegal and unethical organ harvesting practices. Visit www.dafoh.org

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We are pleased to provide free full text access to articles we select from the journals 'American Journal of Transplantation', 'Nephrology', 'Hemodialysis International' and 'Seminars in Dialysis'. Our thanks to the people at Blackwell Publishing for their support of Nephrology Now.

For many other of our selections, users will need individual or institutional subscriptions to access full text. Abstracts are freely available and where noted, some articles also have free full text access. Readers from developing nations can obtain full text access to some journals through the HINARI initiative and the Oxford Journals program.

Nephrology Now ISSN 1911-8880