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Welcome to Nephrology Now, a monthly list of the most pertinent and/or potentionally controversial articles in clinical Nephrology. These articles are selected from a wide range of journals from throughout the Nephrology and Internal Medicine literature. We also include a selection of review articles, opinion pieces and cases that may be of interest.

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Conference Alert

25th Annual Meeting of the International Society of Blood Purification
Prague, Czech Republic, September 15 - 17, 2007.
For program details visit: www.isbp2007.org
Deadline for early registration and abstract submission has been delayed until June 20, 2007.

Original Research - General Nephrology

Nissen, SE, Wolski, K.
Effect of Rosiglitazone on the Risk of Myocardial Infarction and Death from Cardiovascular Causes.
N Engl J Med 2007 Published online May 21, 2007 (10.1056/NEJMoa072761)
[Free Abstract] [Free Full Text] [Free NEJM Commentary] [Free Lancet Commentary] [Discuss]

Askie LM, Duley L, Henderson-Smart DJ et al.
Antiplatelet agents for prevention of pre-eclampsia: a meta-analysis of individual patient data.
The Lancet 2007; 369:1791-1798. [Free Abstract] [Full Text]

Bell M, SWING, Granath F et al.
Continuous renal replacement therapy is associated with less chronic renal failure than intermittent haemodialysis after acute renal failure.
Intensive Care Med 2007; 33(5):773-80. Epub 2007 Mar 16.
[Free Abstract] [Full Text] [Discuss]

Brunori G, Viola BF, Parrinello G.
Efficacy and Safety of a Very-Low-Protein Diet When Postponing Dialysis in the Elderly: A Prospective Randomized Multicenter Controlled Study.
AJKD 2007; 49(5); 569-580. [Free Full Text]

Campbell CL, Smyth S, Montalescot G et al.
Aspirin Dose for the Prevention of Cardiovascular Disease A Systematic Review.
JAMA. 2007;297:2018-2024. [Free Abstract] [Full Text] [JAMA Author in the Room]

Coppo R, Peruzzi L, Amore, A et al.
IgACE: A Placebo-Controlled, Randomized Trial of Angiotensin-Converting Enzyme Inhibitors in Children and Young People with IgA Nephropathy and Moderate Proteinuria.
J Am Soc Nephrol 2007; 18: 1880-1888. [Free Abstract] [Full Text] [Commentary]

Darmon M, Thiery G, Ciroldi M et al.
Should dialysis be offered to cancer patients with acute kidney injury?
Intensive Care Med 2007; 33; 765-772. [Free Abstract] [Full Text]

Hou FF, Xie D, Zhang X et al.
Renoprotection of Optimal Antiproteinuric Doses (ROAD) Study: A Randomized Controlled Study of Benazepril and Losartan in Chronic Renal Insufficiency.
J Am Soc Nephrol 2007 18: 1889-1898. [Free Abstract] [Full Text]

Jha V, Ganguli A, Saha TK et al.
A Randomized, Controlled Trial of Steroids and Cyclophosphamide in Adults with Nephrotic Syndrome Caused by Idiopathic Membranous Nephropathy.
J Am Soc Nephrol 2007; 18: 1899-1904. [Free Abstract] [Full Text] [Discuss]

Lee T, Barker J, Allon M.
Comparison of Survival of Upper Arm Arteriovenous Fistulas and Grafts after Failed Forearm Fistula.
J Am Soc Nephrol 2007; 18: 1936-1941. [Free Abstract] [Full Text]

Recio-Mayoral A, Chaparro M, Prado B et al.
The reno-protective effect of hydration with sodium bicarbonate plus N-acetylcysteine in patients undergoing emergency percutaneous coronary intervention: the RENO Study.
J Am Coll Cardiol. 2007 Mar 27;49(12):1283-8. Epub 2007 Mar 12.
[Free Abstract] [Full Text]

Wijeysundera DN, Karkouti K, Dupuis J et al.
Derivation and Validation of a Simplified Predictive Index for Renal Replacement Therapy After Cardiac Surgery.
JAMA. 2007; 297:1801-1809. [Free Abstract] [Full Text]

Original Research - Transplantation

Hanif F, Abayasekaram K, Willcocks L et al.
The quality of information about kidney transplantation on the World Wide Web.
Clinical Transplantation 2007; 21: 371-376. [Free Abstract] [Full Text] [Discuss]

Vincenti F, Friman S, Scheuermann E et al.
Results of an International, Randomized Trial Comparing Glucose Metabolism Disorders and Outcome with Cyclosporine Versus Tacrolimus.
Am J Transplant 2007; 7:1506-1514. [Free Abstract] [Full Text]

Wali RK, Mohanlal V, Ramos E et al.
Early Withdrawal of Calcineurin Inhibitors and Rescue Immunosuppression with Sirolimus-Based Therapy in Renal Transplant Recipients with Moderate to Severe Renal Dysfunction.
Am J Transplant 2007; 7: 1572-1583. [Free Abstract] [Full Text]

Opinions

Bargman JM
Why are rheumatologists treating lupus nephritis?
Nature Clinical Practice Nephrology 2007; 3: 296-297. [Free Full Text]

Cunningham J.
Bisphosphonates in the renal patient.
Nephrol Dial Transplant 2007; 22: 1505-1507. [Free Full Text]

Reviews

Ng TG, Johnson DW, Hawley CM.
Is it time to revisit residual renal function in haemodialysis?
Nephrology 2007; 12: 209–217. [Free Full Text]
Full text access provided by Blackwell Publishing.

Adrogue, Horacio J., Madias, Nicolaos E.
Sodium and Potassium in the Pathogenesis of Hypertension.
N Engl J Med 2007; 356: 1966-1978. [Free Abstract]

Hladunewich M, Karumanchi SA, Lafayette R.
Pathophysiology of the Clinical Manifestations of Preeclampsia.
Clin J Am Soc Nephrol 2007 2: 543-549. [Full Text]

Ellison DH, Berl T.
The Syndrome of Inappropriate Antidiuresis.
N Engl J Med 2007; 356: 2064-72. [Free Abstract] [Full Text]

Cases

van den Bosch MA et al.
Quiz page. Fibromuscular dysplasia of the right renal artery.
Am J Kidney Dis. 2007 May;49(5):A43-4. [Free Case]

Educational Tools

NEJM Video in Clinical Medicine
Central Vein Catheterization [Access]

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We are pleased to announce free full text access to articles we select from the journals 'Nephrology', 'Hemodialysis International' and 'Seminars in Dialysis'. Our thanks to the people at Blackwell Publishing for their support of Nephrology Now.

For many other of our selections, users will need individual or institutional subscriptions to access full text. Abstracts are freely available and where noted, some articles also have free full text access. Readers from developing nations can obtain full text access to some journals through the HINARI initiative and the Oxford Journals program.

Nephrology Now ISSN 1911-8880