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This newsletter is supported through unrestricted funding provided by Genzyme Corporation.

Welcome to Nephrology Now, a monthly list of the most pertinent and/or potentionally controversial articles in clinical Nephrology. These articles are selected from a wide range of journals from throughout the Nephrology and Internal Medicine literature. We also include a selection of review articles, opinion pieces and cases that may be of interest.

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Nephrology Now: an Online Journal Club
Join others from around the world to discuss articles mentioned in each issue of Nephrology Now. This month's article for discussion is Bennett CL et al. Venous thromboembolism and mortality associated with recombinant erythropoietin and darbepoetin administration for the treatment of cancer-associated anemia. JAMA. 2008 Feb 27;299(8):914-24. Click here to join in...

Original Research - General Nephrology

Bagshaw SM et al.
Continuous versus intermittent renal replacement therapy for critically ill patients with acute kidney injury: a meta-analysis.
Crit Care Med. 2008 Feb;36(2):610-7. [Free Abstract] [Full Text]

Bennett CL et al.
Venous thromboembolism and mortality associated with recombinant erythropoietin and darbepoetin administration for the treatment of cancer-associated anemia.
JAMA. 2008 Feb 27;299(8):914-24. [Free Abstract] [Full Text] [Discuss]

Catena C et al.
Cardiovascular outcomes in patients with primary aldosteronism after treatment.
Arch Intern Med. 2008 Jan 14;168(1):80-5. [Free Abstract] [Full Text]

Gulati S et al.
Tacrolimus: a new therapy for steroid-resistant nephrotic syndrome in children.
Nephrol Dial Transplant. 2008 Mar;23(3):910-3. [Free Abstract] [Full Text]

Kelly AM et al.
Meta-analysis: effectiveness of drugs for preventing contrast-induced nephropathy.
Ann Intern Med. 2008 Feb 19;148(4):284-94. [Free Abstract] [Full Text]

Kovesdy CP et al.
Association of activated vitamin D treatment and mortality in chronic kidney disease.
Arch Intern Med. 2008 Feb 25;168(4):397-403. [Free Abstract] [Full Text]

Schetz M et al.
Tight blood glucose control is renoprotective in critically ill patients.
J Am Soc Nephrol. 2008 Mar;19(3):571-8. [Free Abstract] [Full Text]

Strippoli GF et al.
Effects of statins in patients with chronic kidney disease: meta-analysis and meta-regression of randomised controlled trials.
BMJ 2008;0(2008):bmj.39472.580984.AEv1. [Free Full Text]

Pannu N et al.
Renal replacement therapy in patients with acute renal failure: a systematic review.
JAMA. 2008 Feb 20;299(7):793-805. [Free Abstract] [Full Text]

Shaw AD et al.
The effect of aprotinin on outcome after coronary-artery bypass grafting.
N Engl J Med. 2008 Feb 21;358(8):784-93. [Free Abstract] [Full Text]

Mouton R et al.
Effect of aprotinin on renal dysfunction in patients undergoing on-pump and off-pump cardiac surgery: a retrospective observational study.
Lancet. 2008 Feb 9;371(9611):475-82. [Free Abstract] [Full Text]

Schneeweiss S et al.
Aprotinin during coronary-artery bypass grafting and risk of death.
N Engl J Med. 2008 Feb 21;358(8):771-83. [Free Abstract] [Full Text]

Ray WA.
Learning from aprotinin--mandatory trials of comparative efficacy and safety needed.
N Engl J Med. 2008 Feb 21;358(8):840-2. [Free Abstract] [Full Text]

Original Research - Transplantation

Cosio FG et al.
Transplant glomerulopathy.
Am J Transplant. 2008 Mar;8(3):492-6. [Free Full Text]
Full text access provided by Blackwell Synergy .

Kukla A et al.
CKD stage-to-stage progression in native and transplant kidney disease.
Nephrol Dial Transplant. 2008 Feb;23(2):693-700. [Free Abstract] [Full Text]

Lemy A et al.
Late onset of bladder urothelial carcinoma after kidney transplantation for end-stage aristolochic acid nephropathy: a case series with 15-year follow-up.
Am J Kidney Dis. 2008 Mar;51(3):471-7. [Free Abstract] [Full Text]

Matas AJ et al.
Posttransplant diabetes mellitus and acute rejection: impact on kidney transplant outcome.
Transplantation. 2008 Feb 15;85(3):338-43. [Free Abstract] [Full Text]

Reviews

Barbey F et al.
Fabry nephropathy: 5 years of enzyme replacement therapy—a short review.
NDT Plus 2008 1(1):11-19. [Free Full Text]

Cohen DL et al.
What Effect Does Potassium Have on Blood Pressure?
J Clin Hypertens. 2008 February;10(2):158-159. [Free Full Text]

Kotanko P et al .
Current state of bioimpedance technologies in dialysis.
Nephrol Dial Transplant. 2008 Mar;23(3):808-12. [Free Full Text]

Cases

Chow KM et al.
Quiz page March 2008: fever, anorexia, and renal failure. TINU syndrome.
Am J Kidney Dis. 2008 Mar;51(3):A39-40. [Free Full Text]

Opinions

Pfeffer MA et al.
Critical Missing Data on Erythropoiesis-Stimulating Agents in CKD: First Beat Placebo.
Am J Kidney Dis. 2008 Mar;51(3):366-9. [Free Full Text]

Images

Colucciello M.
Images in clinical medicine. Retinal arteriolar cholesterol emboli.
N Engl J Med. 2008 Feb 21;358(8):826. [Free Full Text]

Pol-Rodriguez MM, Wanner M, Bhat P, Grossman ME.
Uremic frost in a critically ill patient.
Kidney Int. 2008 Mar;73(6):790. [Full Text]

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We are pleased to provide free full text access to articles we select from the journals 'American Journal of Transplantation', 'Nephrology', 'Hemodialysis International' and 'Seminars in Dialysis'. Our thanks to the people at Blackwell Publishing for their support of Nephrology Now.

For many other of our selections, users will need individual or institutional subscriptions to access full text. Abstracts are freely available and where noted, some articles also have free full text access. Readers from developing nations can obtain full text access to some journals through the HINARI initiative and the Oxford Journals program.

Nephrology Now ISSN 1911-8880