Archive for February, 2012

February 26, 2012

World Kidney Day 2012: The Global Role of Kidney Transplantation

.   .   

This article reflects on the success of kidney transplantation for the therapy of ESRD to commemorate World Kidney Day on March 8, 2012.

Comments Off on World Kidney Day 2012: The Global Role of Kidney Transplantation Posted in Renal Transplantation
February 26, 2012

Treatment of chronic kidney disease

.   .   

This article reviews the therapeutic options to delay the progression of chronic kidney disease.  

Comments Off on Treatment of chronic kidney disease Posted in Chronic Kidney Disease
February 26, 2012

Choosing peritoneal dialysis reduces the risk of invasive access interventions

.   .   

This prospective multicentre Canadian study followed 369 dialysis patients for an average of 1.3 years (224 patients chose PD and 145 chose HD).  The authors found that the PD group required fewer access interventions to maintain dialysis access (2.5 versus 3.1 interventions per patient, adjusted odds ratio of 0.79 for PD versus HD, P = […]

Comments Off on Choosing peritoneal dialysis reduces the risk of invasive access interventions Posted in Peritoneal Dialysis
February 26, 2012

Randomized Controlled Trial Comparing Mupirocin and Polysporin Triple Ointments in Peritoneal Dialysis Patients: The MP3 Study

.   .   

This double-blind multicentre RCT studied the effectiveness of topical Polysporin Triple ointment as compared to mupirocin to peritoneal dialysis catheter exit sites.  Twice the number of patients experienced redness at the exit site in the Polysporin Triple group (14 versus 6, P=0.10) with a higher rate of fungal exit site infection (0.07 versus 0.01; P=0.02) […]

Comments Off on Randomized Controlled Trial Comparing Mupirocin and Polysporin Triple Ointments in Peritoneal Dialysis Patients: The MP3 Study Posted in Peritoneal Dialysis
February 26, 2012

Three-Year Outcomes from BENEFIT, a Randomized, Active-Controlled, Parallel-Group Study in Adult Kidney Transplant Recipients

.   .   

BENEFIT is a randomized controlled trial comparing two different doses of belatacept, a costimulatory blocker, to standard therapy with cyclosporine in de novo kidney transplant patients. Earlier results from this study showed a higher acute rejection rate with belatacept. Nonetheless, at three years, renal function was significantly better in belatacept-treated patents.

Comments Off on Three-Year Outcomes from BENEFIT, a Randomized, Active-Controlled, Parallel-Group Study in Adult Kidney Transplant Recipients Posted in Renal Transplantation
February 26, 2012

Ureteral Stents Are Associated With Reduced Risk of Ureteral Complications After Kidney Transplantation: A Large Single Center Experience

.   .   

Insertion of a double-J stent into the transplant ureter at the time of surgery reduces the risk of ureteric stricture. In this single-centre study, the decision to insert a ureteral stent or not was made by surgeons at the time of transplantation. There was a significant reduction in the risk of stricture, but only in […]

Comments Off on Ureteral Stents Are Associated With Reduced Risk of Ureteral Complications After Kidney Transplantation: A Large Single Center Experience Posted in Renal Transplantation
February 26, 2012

Recurrent Dense Deposit Disease After Renal Transplantation: An Emerging Role for Complementary Therapies

.   .   

Membranoproliferative glomerulonephritis type II, or dense deposit disease, is a rare type of renal disease caused by excessive complement deposition in the kidney. It is also associated with a high rate of recurrence post-transplant. In this case report, a patient developed recurrent dense deposit disease shortly after transplant. Despite aggressive treatment, renal function worsened and […]

Comments Off on Recurrent Dense Deposit Disease After Renal Transplantation: An Emerging Role for Complementary Therapies Posted in Renal Transplantation
February 26, 2012

Testosterone deficiency is a cause of anemia and reduced responsiveness to erythropoiesis-stimulating agents in men with chronic kidney disease

.   .   

This observational study assessed a) the association between testosterone levels and hemoglobin in nondialysed CKD Stages 1-5 ESA-naive male patients as well as the association between testosterone levels and ESA dose in ESA-treated males undergoing hemodialysis.  CKD patients with lower testosterone values were 5.3 times more likely to be anemic.  In patients undergoing HD, higher […]

Comments Off on Testosterone deficiency is a cause of anemia and reduced responsiveness to erythropoiesis-stimulating agents in men with chronic kidney disease Posted in Anemia