Archive for September, 2013

September 8, 2013

A single-blind randomized controlled trial to evaluate the effect of 6 months of progressive aerobic exercise training in patients with uraemic restless legs syndrome

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This small single-center study showed that a 6-month intradialytic progressive exercise training program reduces severity of restless leg syndrome in HD patients.

Comments Off on A single-blind randomized controlled trial to evaluate the effect of 6 months of progressive aerobic exercise training in patients with uraemic restless legs syndrome Posted in Hemodialysis
September 8, 2013

The Pathogenesis of Lupus Nephritis

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This review goes into extensive detail on the pathogenesis of lupus nephritis and provides the rationale for treatment. Full text kindly provided by the American Society of Nephrology.

1 Comment Posted in Lupus, Review
September 8, 2013

Risks and benefits of intensive blood pressure lowering in patients with type 2 diabetes

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This review discusses the basis for the blood pressure target of < 130/80 mm Hg for patients with hypertension and diabetes.

1 Comment Posted in Diabetes, Hypertension
September 8, 2013

Effects of intensive blood pressure lowering on the progression of chronic kidney disease: a systematic review and meta-analysis

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In patient with chronic kidney disease, this meta-analysis identified a 27% reduction (HR 0.73, 95% CI 0.62–0.86) in ESRD with intensive blood pressure lowering <130/80, whereas no effect was seen in patients without proteinuria. The accompanying editorial “Blood pressure targets in chronic kidney disease: Does proteinuria dictate how low we go?” discusses the interpretation of […]

4 Comments Posted in Chronic Kidney Disease, Hypertension
September 7, 2013

Use of Antihypertensive Medications and Breast Cancer Risk Among Women Aged 55 to 74 Years

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This case-control study identified an association between >10 years of calcium-channel blockers use and a higher risk of ductal breast cancer. The associated editorial Calcium-Channel Blockers and Breast Cancer: A Hypothesis Revived discusses how this finding may be interpreted.

Comments Off on Use of Antihypertensive Medications and Breast Cancer Risk Among Women Aged 55 to 74 Years Posted in Hypertension, Internal Medicine for Nephrologists