Association Between a Chloride-Liberal vs Chloride-Restrictive Intravenous Fluid Administration Strategy and Kidney Injury in Critically Ill Adults
This prospective, open label trial studied 760 consecutive ICU patients that preferentially received chloride-poor (eg lactate solution, balanced solution or 20% albumin) intravenous solutions. The primary outcomes showed that the use of chloride-restricted solutions was associated with a decreased incidence of AKI and use of RRT. There was no difference mortality, length of stay or need for RRT after discharge.
- Randomized Trial of Bicarbonate or Saline Study for the Prevention of Contrast-Induced Nephropathy in Patients with CKD
- AZA/Tacrolimus Is Associated with Similar Outcomes as MMF/Tacrolimus among Renal Transplant Recipients.
- Histidine-tryptophan-ketoglutarate (HTK) is associated with reduced graft survival of deceased donor kidney transplants.