Archive for the ‘Bone Mineral Metabolism’ Category

May 1, 2010

Interventions for bone disease in children with chronic kidney disease.

Geary DF, Hodson EM, Craig JC.   Cochrane Database Syst Rev.   2010 Jan 20;(1):CD008327

This systematic review of interventions for bone disease in children with CKD concludes that all examined vitamin D formulations reduce PTH levels and that sevelamer as compared to calcium-based binders reduced serum calcium and hypercalcemic events. However, no reduction in hard clinical endpoints was identified.

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No Comments Posted in Bone Mineral Metabolism, Chronic Kidney Disease, Pediatric Nephrology
May 1, 2010

Oral Phosphate Binders in Patients with Kidney Failure

Tonelli M, Pannu N, Manns B.   N Engl J Med.   2010 Apr 8;362(14):1312-24

This concise review discusses the rationale for the use of phosphate binders in kidney disease and summarizes therapeutic strategies.

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1 Comment Posted in Bone Mineral Metabolism, Review
February 12, 2010

Second Chances in Mineral Metabolism

Wolf M.   Clin J Am Soc Nephrol.   2010 Jan;5(1):1-3

In this succinct editorial, Dr. Wolf reinforces the rationale for performing proper randomized controlled trials in bone mineral metabolism before changing clinical practice.  In addition, he provides insight into a first-in-class substudy of the ACHIEVE study which looks at the effects of cinacalcet and activated Vitamin D on FGF23 levels in ESRD. Free full text [...]

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1 Comment Posted in Bone Mineral Metabolism
August 21, 2009

KDIGO Clinical Practice Guideline for the Diagnosis, Evaluation, Prevention, and Treatment of Chronic Kidney Disease–Mineral and Bone Disorder (CKD–MBD)

These clinical practice guidelines developed by KDIGO are designed to address the diagnosis, evaluation, prevention and treatment of CKD related disorders of bone mineral metabolism.

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1 Comment Posted in Bone Mineral Metabolism, Clinical Practice Guidelines, Vascular Disease/Calcification
March 1, 2009

Salivary phosphate-binding chewing gum reduces hyperphosphatemia in dialysis patients.

Savica V, Calò LA, Monardo P, Davis PA, Granata A, Santoro D, Savica R, Musolino R, Comelli MC, Bellinghieri G.   J Am Soc Nephrol.   2009 Mar;20(3):639-44

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No Comments Posted in Bone Mineral Metabolism
March 1, 2009

Salivary phosphorus binding: a novel approach to control hyperphosphatemia.

Eknoyan G.   J Am Soc Nephrol.   2009 Mar;20(3):460-2

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No Comments Posted in Bone Mineral Metabolism
March 1, 2009

Effect of Food Additives on Hyperphosphatemia Among Patients With End-stage Renal Disease A Randomized Controlled Trial.

Sullivan C, Sayre SS, Leon JB, Machekano R, Love TE, Porter D, Marbury M, Sehgal AR.   JAMA.   2009 Feb 11;301(6):629-35

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No Comments Posted in Bone Mineral Metabolism
November 1, 2008

Serum alkaline phosphatase predicts mortality among maintenance hemodialysis patients.

Regidor DL, Kovesdy CP, Mehrotra R, Rambod M, Jing J, McAllister CJ, Van Wyck D, Kopple JD, Kalantar-Zadeh K.   J Am Soc Nephrol.   2008 Nov;19(11):2193-203

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No Comments Posted in Bone Mineral Metabolism
October 1, 2008

Oral active vitamin D is associated with improved survival in hemodialysis patients.

Naves-Díaz M, Alvarez-Hernández D, Passlick-Deetjen J, Guinsburg A, Marelli C, Rodriguez-Puyol D, Cannata-Andía JB.   Kidney Int.   2008 Oct;74(8):1070-8

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No Comments Posted in Bone Mineral Metabolism
October 1, 2008

Vitamin D in chronic kidney disease: is the jury in?

de Boer IH, Kestenbaum B.   Kidney Int.   2008 Oct;74(8):985-7

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No Comments Posted in Bone Mineral Metabolism
August 1, 2008

Association of oral calcitriol with improved survival in nondialyzed CKD.

Shoben AB, Rudser KD, de Boer IH, Young B, Kestenbaum B.   J Am Soc Nephrol.   2008 Aug;19(8):1613-9

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No Comments Posted in Bone Mineral Metabolism
August 1, 2008

Active vitamin D and survival.

Wolf M.   J Am Soc Nephrol.   2008 Aug;19(8):1442-3

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No Comments Posted in Bone Mineral Metabolism
July 1, 2008

A randomized, double-blind, placebo-controlled trial of niacinamide for reduction of phosphorus in hemodialysis patients.

Cheng SC, Young DO, Huang Y, Delmez JA, Coyne DW.   Clin J Am Soc Nephrol.   2008 Jul;3(4):1131-8

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No Comments Posted in Bone Mineral Metabolism
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