July 20, 2010
Van Wert R, Friedrich JO, Scales DC, Wald R, Adhikari NK, University of Toronto Acute Kidney Injury Research Group. Crit Care Med. 2010 May;38(5):1360-9
This meta-analysis examining high-dose renal replacement therapy in acute kidney injury did not show any improvement in patient survival or recovery of renal function.
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November 22, 2009
RENAL Replacement Therapy Study Investigators, Bellomo R, Cass A, Cole L, Finfer S, Gallagher M, Lo S, McArthur C, McGuinness S, Myburgh J, Norton R, Scheinkestel C, Su S. N Engl J Med. 2009 Oct 22;361(17):1627-38
This multicenter, randomized trial compared the effect of CRRT, delivered at two different levels of intensity (40 ml/kg vs 25 ml/kg), on 90-day mortality among critically ill patients with acute kidney injury. Treatment with higher-intensity continuous renal-replacement therapy did not reduce mortality at 90 days.
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October 18, 2009
Wald R, Quinn RR, Luo J, Li P, Scales DC, Mamdani MM, Ray JG, University of Toronto Acute Kidney Injury Research Group. JAMA. 2009 Sep 16;302(11):1179-85
The purpose of this Canadian population-based cohort study was to assess the risk of chronic dialysis and all-cause mortality in individuals who experienced an episode of acute kidney injury requiring dialysis. The authors concluded that acute kidney injury necessitating in-hospital dialysis was associated with an increased risk of chronic dialysis but not all-cause mortality.
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August 21, 2009
Brienza N, Giglio MT, Marucci M, Fiore T. Crit Care Med. 2009 Jun;37(6):2079-90
This meta-analysis sought to address the question of whether perioperative hemodynamic optimization could reduce postoperative renal dysfunction. The results suggest a decreased risk of renal impairment and post-operative mortality.
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July 10, 2009
Faulhaber-Walter R, Hafer C, Jahr N, Vahlbruch J, Hoy L, Haller H, Fliser D, Kielstein JT. Nephrol Dial Transplant. 2009 Jul;24(7):2179-86
This prospective randomized parallel group trial aimed to assess mortality and renal recovery of patients with acute kidney injury (AKI) receiving either standard (SED) or intensified extended dialysis (IED) therapy in the intensive care unit. 156 patients with AKI were randomly assigned to receive standard dialysis or intensified dialysis. No differences between intensified and standard [...]
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May 1, 2009
Liu KD. Am J Kidney Dis. 2009 May;53(5):898-910
April 1, 2009
Payen D, Mateo J, Cavaillon JM, Fraisse F, Floriot C, Vicaut E, Hemofiltration and Sepsis Group of the Collège National de Réanimation et de Médecine d'Urgence des Hôpitaux extra-Universitaires. Crit Care Med. 2009 Mar;37(3):803-10
November 1, 2008
Humes HD, Ding F, Song JH. Am J Kidney Dis. 2008 Oct;52(4):649-52
November 1, 2008
Ronco C, Cruz D, Oudemans van Straaten H, Honore P, House A, Bin D, Gibney N. Crit Care. 2008;12(5):308
June 1, 2008
VA/NIH Acute Renal Failure Trial Network, Palevsky PM, Zhang JH, O'Connor TZ, Chertow GM, Crowley ST, Choudhury D, Finkel K, Kellum JA, Paganini E, Schein RM, Smith MW, Swanson KM, Thompson BT, Vijayan A, Watnick S, Star RA, Peduzzi P. N Engl J Med. 2008 Jul 3;359(1):7-20
June 1, 2008
Bonventre JV. N Engl J Med. 2008 Jul 3;359(1):82-4
June 1, 2008
Tolwani AJ, Campbell RC, Stofan BS, Lai KR, Oster RA, Wille KM. J Am Soc Nephrol. 2008 Jun;19(6):1233-8
June 1, 2008
Mehta RL, Bouchard J. J Am Soc Nephrol. 2008 Jun;19(6):1046-8
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