Archive for the ‘Critical Care’ Category

November 16, 2014

Successful Delivery of RRT in Ebola Virus Disease

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This timely article describes the protocol used at Emory University Hospital to provide dialysis in a patient with Ebola virus and proposes clinical practice guidelines for acute dialysis in this infection.

Comments Off on Successful Delivery of RRT in Ebola Virus Disease Posted in Acute Kidney Injury, Clinical Nephrology, Critical Care
April 1, 2013

Association of hydroxyethyl starch administration with mortality and acute kidney injury in critically ill patients requiring volume resuscitation: a systematic review and meta-analysis.

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Recently, 7 trials investigating the role of hydroxyethyl starch in the critically ill were retracted because of scientific misconduct. This meta-analysis, which excludes these studies, indicates an increased risk of death and acute kidney injury in critically ill patients requiring acute volume resuscitation.

Comments Off on Association of hydroxyethyl starch administration with mortality and acute kidney injury in critically ill patients requiring volume resuscitation: a systematic review and meta-analysis. Posted in Acute Kidney Injury, Critical Care
November 25, 2012

Ultrafiltration in Decompensated Heart Failure with Cardiorenal Syndrome

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This randomized controlled trial compared ultrafiltration versus stepped pharmacologic therapy in patients with acute decompensated heart failure and a decline in kidney function (cardiorenal syndrome). Ultrafiltration was found to be inferior in achieving the bivariate endpoint in change in serum creatinine and body weight after 96 hours. The ultrafiltration group experienced a higher rate of […]

Comments Off on Ultrafiltration in Decompensated Heart Failure with Cardiorenal Syndrome Posted in Acute Kidney Injury, Cardiorenal Syndrome, Critical Care
January 28, 2012

Decongestive Treatment of Acute Decompensated Heart Failure: Cardiorenal Implications of Ultrafiltration and Diuretics

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This review discusses the role of diuretics and ultrafiltration in acute decompensated heart failure.

1 Comment Posted in Critical Care, Internal Medicine for Nephrologists, Review
February 8, 2011

Intra-abdominal Hypertension and Abdominal Compartment Syndrome

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This concise review discusses intra-abdominal hypertension and abdominal compartment syndrome as a potential cause of acute kidney injury in the critically ill.

1 Comment Posted in Acute Kidney Injury, Critical Care, Review
July 20, 2010

High-dose renal replacement therapy for acute kidney injury: Systematic review and meta-analysis.

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This meta-analysis examining high-dose renal replacement therapy in acute kidney injury did not show any improvement in patient survival or recovery of renal function.

1 Comment Posted in Critical Care, Hemodialysis
November 22, 2009

Intensity of Continuous Renal-Replacement Therapy in Critically Ill Patients

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This multicenter, randomized trial compared the effect of CRRT, delivered at two different levels of intensity (40 ml/kg vs 25 ml/kg), on 90-day mortality among critically ill patients with acute kidney injury. Treatment with higher-intensity continuous renal-replacement therapy did not reduce mortality at 90 days.

Comments Off on Intensity of Continuous Renal-Replacement Therapy in Critically Ill Patients Posted in Acute Kidney Injury, Critical Care
October 18, 2009

Chronic Dialysis and Death Among Survivors of Acute Kidney Injury Requiring Dialysis

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The purpose of this Canadian population-based cohort study was to assess the risk of chronic dialysis and all-cause mortality in individuals who experienced an episode of acute kidney injury requiring dialysis.   The authors concluded that acute kidney injury necessitating in-hospital dialysis was associated with an increased risk of chronic dialysis but not all-cause mortality.

Comments Off on Chronic Dialysis and Death Among Survivors of Acute Kidney Injury Requiring Dialysis Posted in Acute Kidney Injury, Critical Care, Hemodialysis
August 21, 2009

Does perioperative hemodynamic optimization protect renal function in surgical patients? A meta-analytic study.

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This meta-analysis sought to address the question of whether perioperative hemodynamic optimization could reduce postoperative renal dysfunction.  The results suggest a decreased risk of renal impairment and post-operative mortality.

1 Comment Posted in Acute Kidney Injury, Critical Care
July 10, 2009

The Hannover Dialysis Outcome study: comparison of standard versus intensified extended dialysis for treatment of patients with acute kidney injury in the intensive care unit

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This prospective randomized parallel group trial aimed to assess mortality and renal recovery of patients with acute kidney injury (AKI) receiving either standard (SED) or intensified extended dialysis (IED) therapy in the intensive care unit. 156 patients with AKI were randomly assigned to receive standard dialysis or intensified dialysis. No differences between intensified and standard […]

Comments Off on The Hannover Dialysis Outcome study: comparison of standard versus intensified extended dialysis for treatment of patients with acute kidney injury in the intensive care unit Posted in Acute Kidney Injury, Critical Care
May 1, 2009

Critical Care Nephrology: Core Curriculum 2009

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Comments Off on Critical Care Nephrology: Core Curriculum 2009 Posted in AJKD Core Curriculum, Critical Care
April 1, 2009

Impact of continuous venovenous hemofiltration on organ failure during the early phase of severe sepsis: a randomized controlled trial.

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Comments Off on Impact of continuous venovenous hemofiltration on organ failure during the early phase of severe sepsis: a randomized controlled trial. Posted in Critical Care
November 1, 2008

Dialysis dosing in critically ill patients with acute kidney injury.

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Comments Off on Dialysis dosing in critically ill patients with acute kidney injury. Posted in Critical Care