Archive for the ‘Fluid & Electrolytes’ Category

September 21, 2015

Electrolyte and Acid–Base Disturbances in Patients with Diabetes Mellitus

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This review nicely summarizes electrolyte and acid-base base abnormalities and their management in patients with diabetes.

No Comments Posted in Clinical Nephrology, Diabetes, Fluid & Electrolytes, General Nephrology
July 13, 2015

Current treatment practice and outcomes. Report of the hyponatremia registry

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This report from the hyponatremia registry highlights the multifaceted and often clinically disparate approach to the management of hyponatremia.  Interestingly, most patients were discharged from hospital still hyponatremic.          

No Comments Posted in Clinical Nephrology, Fluid & Electrolytes, General Nephrology
July 13, 2015

Vasopressin Antagonists

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This is a nice review summarizes the literature on the vasopressin antagonists – both historically and clinically.    

No Comments Posted in Clinical Nephrology, Fluid & Electrolytes
May 8, 2015

Molecular physiology of water balance

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This review describes the recent progress in understanding the roles of selected gene products in the regulation of water balance and their relevance in clinical practice.    

No Comments Posted in Clinical Nephrology, Fluid & Electrolytes, General Nephrology
March 18, 2015

Acid–Base Problems in Diabetic Ketoacidosis

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This review focuses on three issues facing clinicians who care for patients with diabetic ketoacidosis: (1) the plasma anion gap, (2) the administration of sodium bicarbonate and (3) the possible contribution of intracellular acidosis to the development of cerebral edema.

No Comments Posted in Clinical Nephrology, Fluid & Electrolytes, General Nephrology, Review
March 18, 2015

Trimethoprim-sulfamethoxazole and risk of sudden death among patients taking spironolactone

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Compared with amoxicillin, trimethoprim-sulfamethoxazole was associated with a  twofold increase of sudden death (adjusted OR 2.46, 95 % CI 1.55-3.90) as a consequence of hyperkalemia in this population-based study of patients over the age of 65 on spironolactone.

No Comments Posted in Clinical Nephrology, Fluid & Electrolytes, General Nephrology
January 24, 2015

Effect of Low Versus High Dialysate Sodium Concentration on Blood Pressure and Endothelial-Derived Vasoregulators During Hemodialysis: A Randomized Crossover Study.

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This interesting study looked at the effect of dialysate sodium concentrations (low (5 mEq/L below serum sodium) versus high (5 mEq/L above serum sodium)) and the effect on blood pressure during dialysis.  The results showed that low sodium dialysate significantly decreased systolic BP and ameliorated intradialytic hypertension. However, longer studies are needed to determine the long-term effects.

Comments Off on Effect of Low Versus High Dialysate Sodium Concentration on Blood Pressure and Endothelial-Derived Vasoregulators During Hemodialysis: A Randomized Crossover Study. Posted in Clinical Nephrology, Fluid & Electrolytes, Hemodialysis
January 24, 2015

Disorders of Plasma Sodium — Causes, Consequences, and Correction

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Comments Off on Disorders of Plasma Sodium — Causes, Consequences, and Correction Posted in Clinical Nephrology, Fluid & Electrolytes
December 17, 2014

Survival advantage of lanthanum carbonate for hemodialysis patients with uncontrolled hyperphosphatemia

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This retrospective study of maintenance hemodialysis patients showed that treatment with lanthanum was independently associated with a reduction in all cause mortality in those patients with uncontrolled hyperphosphatemia.

Comments Off on Survival advantage of lanthanum carbonate for hemodialysis patients with uncontrolled hyperphosphatemia Posted in Clinical Trial Results, Fluid & Electrolytes, General Nephrology, Hemodialysis
November 16, 2014

Integration of Acid–Base and Electrolyte Disorders

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This review, appropriate for trainees and practicing physicians, provides an approach to the diagnosis of acid-base disorders.

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April 19, 2014

Clinical practice guideline on diagnosis and treatment of hyponatremia

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These multispecialty guidelines provide a very practical approach to management of this very common clinical disorder.

2 Comments Posted in Clinical Practice Guidelines, Fluid & Electrolytes
August 23, 2013

Role of Vaptans in the Management of Hyponatremia

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In order to use vasopressin receptor antagonists safely, one requires a comprehensive understanding of their indications and contraindications. This review provides an in-depth look at vaptans and their role in the management of euvolemic and hypervolemic hyponatremia.

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January 28, 2013

Proximal renal tubular acidosis: a not so rare disorder of multiple etiologies

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This nice review discusses etiology and management of proximal renal tubular acidosis.

Comments Off on Proximal renal tubular acidosis: a not so rare disorder of multiple etiologies Posted in Fluid & Electrolytes, Review