November 12, 2011
The late breaking clinical trials session from the 2011 American Society of Nephrology meeting was held on November 12, 2011. The following are summaries of some of the clinical trial results. Access to the full details of these studies awaits publication in peer reviewed journals. Charmaine E. Lok et al. The Fish Oil Inhibition of Stenosis [...]
June 15, 2011
Manno C, Bonifati C, Torres DD, Campobasso N, Schena FP. Am J Kidney Dis. 2011 Jun;57(6):850-5
This double-blind randomized controlled trial of 162 patients with eGFR > 60 ml/min showed that desmopressin decreased the bleeding rate post-renal biopsy. Of note, the control group had a very high bleeding rate of approximately 30% which may not be representative of many centers’ experience.
April 24, 2011
Haller H, Ito S, Izzo JL Jr, Januszewicz A, Katayama S, Menne J, Mimran A, Rabelink TJ, Ritz E, Ruilope LM, Rump LC, Viberti G, ROADMAP Trial Investigators. N Engl J Med. 2011 Mar 10;364(10):907-17
This large randomized multicentre trial showed delayed onset of microalbuminuria in Type 2 diabetics with normoalbuminuria that were treated with olmesartan 40 mg daily as compared to the placebo group, but a higher rate of fatal cardiovascular events in those with preexisting heart disease. Editorial http://www.nejm.org/doi/full/10.1056/NEJMe1014147 UKidney Discussion http://qx.md/y
July 20, 2010
Muirhead N. Ann Intern Med. 2010 Jun 1;152(11):721-5
This article highlights the findings of several key trials that were published in the field of chronic kidney disease in 2009.
November 22, 2009
FDA notified healthcare professionals of revisions to the prescribing information for Byetta (exenatide) to include information on post-marketing reports of altered kidney function, including acute renal failure and insufficiency. Byetta, an incretin-mimetic, is approved as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.
November 22, 2009
Hutchison CA, Basnayake K, Cockwell P. Nat Rev Nephrol. 2009 Nov;5(11):621-8
This review examines the evidence associated with the use of the free light chain assay.
September 13, 2009
Free full text access to the Harrison’s chapter “Alterations in Renal and Urinary Tract Function”.
August 20, 2009
Kripalani M, Shawcross J, Reilly J, Main J. BMJ. 2009 Jul 3;339:b2452
This review discusses the renal impact of lithium usage and offers guidance on monitoring, drug interactions, and when to consider discontinuation.
May 1, 2009
West M, Nicholls K, Mehta A, Clarke JT, Steiner R, Beck M, Barshop BA, Rhead W, Mensah R, Ries M, Schiffmann R. J Am Soc Nephrol. 2009 May;20(5):1132-9
April 1, 2009
Burgess E, Muirhead N, Rene de Cotret P, Chiu A, Pichette V, Tobe S, SMART (Supra Maximal Atacand Renal Trial) Investigators. J Am Soc Nephrol. 2009 Apr;20(4):893-900
April 1, 2009
El Fakih R, Saliba W, Mortada R. Am J Kidney Dis. 2009 Apr;53(4):xxxvii-xxxix
March 1, 2009
Chartapisak W, Opastiraku S, Willis NS, Craig JC, Hodson EM. Arch Dis Child. 2009 Feb;94(2):132-7
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