Archive for the ‘Hemodialysis’ Category

February 12, 2010

Stent Graft versus Balloon Angioplasty for Failing Dialysis-Access Grafts

Haskal ZJ, Trerotola S, Dolmatch B, Schuman E, Altman S, Mietling S, Berman S, McLennan G, Trimmer C, Ross J, Vesely T.   N Engl J Med.   2010 Feb 11;362(6):494-503

This important RCT concludes that in treatment of venous anastomotic stenosis of hemodialysis grafts, angioplasty plus placement of a stent provides better longer-term patency and freedom from repeat interventions than balloon angioplasty.
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No Comments Posted in Hemodialysis, Vascular Access
February 12, 2010

AURORA: Is There a Role for Statin Therapy in Dialysis Patients

Shurraw S, Tonelli M.   Am J Kidney Dis.   2010 Feb;55(2):237-40

This review discusses the role of statins in dialysis patients and offers insight into the interpretation of AURORA and the 4D study.
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1 Comment Posted in Hemodialysis, Review
January 11, 2010

Effect of Hemodialysis before Transplant Surgery on Renal Allograft Function – A Pair of Randomized Controlled Trials

Kikić Z, Lorenz M, Sunder-Plassmann G, Schillinger M, Regele H, Györi G, Mühlbacher F, Winkelmayer WC, Böhmig GA.   Transplantation.   2009 Dec 27;88(12):1377-85

Previous studies have suggested that hemodialysis immediately before transplant surgery may increase the risk of delayed graft function. In this RCT, patients were randomized to be dialyzed or not pre-transplant; patients with a potassium > 5.0 were randomized to citrate or heparin
anticoagulation. There were no differences in the incidence of DGF, acute rejection or early [...]

No Comments Posted in Hemodialysis, Renal Transplantation
December 14, 2009

Home Hemodialysis, Daily Hemodialysis, and Nocturnal Hemodialysis: Core Curriculum 2009

Perl J, Chan CT.   Am J Kidney Dis.   2009 Dec;54(6):1171-84

This next addition to the AJKD Core Curriculum series provides a detailed overview of the topic of “Home Hemodialysis, Daily Hemodialysis and Nocturnal Hemodialysis”.
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No Comments Posted in Educational Resource, Hemodialysis
November 22, 2009

Cardiovascular and noncardiovascular mortality among patients starting dialysis.

de Jager DJ, Grootendorst DC, Jager KJ, van Dijk PC, Tomas LM, Ansell D, Collart F, Finne P, Heaf JG, De Meester J, Wetzels JF, Rosendaal FR, Dekker FW.   JAMA.   2009 Oct 28;302(16):1782-9

This study evaluated whether the high overall mortality in patients starting dialysis is a consequence of increased cardiovascular mortality risk only or whether noncardiovascular mortality is equally increased. In this analysis, patients starting dialysis were found to have an increased risk of death not specifically caused by excess cardiovascular mortality.
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No Comments Posted in Hemodialysis, Peritoneal Dialysis, Vascular Disease/Calcification
November 22, 2009

Functional status of elderly adults before and after initiation of dialysis.

Kurella Tamura M, Covinsky KE, Chertow GM, Yaffe K, Landefeld CS, McCulloch CE.   N Engl J Med.   2009 Oct 15;361(16):1539-47

This paper demonstrates that among nursing home residents with ESRD, the initiation of dialysis is associated with a substantial and sustained decline in functional status.
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1 Comment Posted in Chronic Kidney Disease, Hemodialysis
October 18, 2009

Chronic Dialysis and Death Among Survivors of Acute Kidney Injury Requiring Dialysis

Wald R, Quinn RR, Luo J, Li P, Scales DC, Mamdani MM, Ray JG, University of Toronto Acute Kidney Injury Research Group.   JAMA.   2009 Sep 16;302(11):1179-85

The purpose of this Canadian population-based cohort study was to assess the risk of chronic dialysis and all-cause mortality in individuals who experienced an episode of acute kidney injury requiring dialysis.   The authors concluded that acute kidney injury necessitating in-hospital dialysis was associated with an increased risk of chronic dialysis but not all-cause mortality.
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No Comments Posted in Acute Renal Failure, Critical Care, Hemodialysis
September 13, 2009

Survival among Nocturnal home Haemodialysis Patients Compared to Kidney Transplant Recipients.

Pauly RP, Gill JS, Rose CL, Asad RA, Chery A, Pierratos A, Chan CT.   Nephrol Dial Transplant.   2009 Sep;24(9):2915-9

This paper compared the results of nocturnal hemodialysis patients at two centres with matched deceased and liver donor transplant patients. Patient survival on nocturnal hemodialysis was similar to deceased donor transplantation, but inferior to live-donor transplantation. This is only a registry analysis and not a RCT. In addition, the dialysis patients were Canadian, while the [...]

No Comments Posted in Hemodialysis, Renal Transplantation
August 21, 2009

Comparison of the prognostic value of dipyridamole and dobutamine myocardial perfusion scintigraphy in hemodialysis patients.

De Vriese AS, De Bacquer DA, Verbeke FH, De Winter O, Franken PR, De Sutter JH, Walgraeve N, Missault L, De Geeter FW.   Kidney Int.   2009 Aug;76(4):428-36

This study compared the use of dobutamine and dipyridamole in cardiac stress testing of patients on hemodialysis.  Although dobutamine induced more pronounced myocardial ischemia than dipyridamole in chronic hemodialysis patients, use of dipyridamole more accurately identifies patients at high risk for subsequent cardiac death or non-fatal CAD.
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1 Comment Posted in Hemodialysis, Vascular Disease/Calcification
August 20, 2009

Staphylococcus aureus Infections in Hemodialysis: What a Nephrologist Should Know

Vandecasteele SJ, Boelaert JR, De Vriese AS.   Clin J Am Soc Nephrol.   2009 Aug;4(8):1388-400

This concise review provides a clinical perspective on Staphylococcus aureus infections in hemodialysis practice.  Free full text access kindly provided by the American Society of Nephrology.
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No Comments Posted in Hemodialysis, Review, Vascular Access
June 10, 2009

Effect of dipyridamole plus aspirin on hemodialysis graft patency

Dixon BS, Beck GJ, Vazquez MA, Greenberg A, Delmez JA, Allon M, Dember LM, Himmelfarb J, Gassman JJ, Greene T, Radeva MK, Davidson IJ, Ikizler TA, Braden GL, Fenves AZ, Kaufman JS, Cotton JR Jr, Martin KJ, McNeil JW, Rahman A, Lawson JH, Whiting JF, Hu B, Meyers CM, Kusek JW, Feldman HI, DAC Study Group.   N Engl J Med.   2009 May 21;360(21):2191-201

This randomized controlled trial provides evidence that treatment with dipyridamole plus aspirin had a modest effect in reducing the risk of stenosis and improving the duration of primary unassisted patency of newly created grafts.

View the Accompanying editorial by C Lok
Antiplatelet therapy and vascular-access patency.
N Engl J Med. 2009 May 21;360(21):2240-2.

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1 Comment Posted in Hemodialysis, Vascular Access
June 9, 2009

The importance of residual kidney function for patients on dialysis: a critical review.

Perl J, Bargman JM.   Am J Kidney Dis.   2009 Jun;53(6):1068-81

This review highlights the evidence to support maintaining residual renal function and its impact on survival and quality of life of dialysis patients.
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No Comments Posted in Hemodialysis, Peritoneal Dialysis, Residual Renal Function
April 1, 2009

Rosuvastatin and cardiovascular events in patients undergoing hemodialysis.

Fellström BC, Jardine AG, Schmieder RE, Holdaas H, Bannister K, Beutler J, Chae DW, Chevaile A, Cobbe SM, Grönhagen-Riska C, De Lima JJ, Lins R, Mayer G, McMahon AW, Parving HH, Remuzzi G, Samuelsson O, Sonkodi S, Sci D, Süleymanlar G, Tsakiris D, Tesar V, Todorov V, Wiecek A, Wüthrich RP, Gottlow M, Johnsson E, Zannad F, AURORA Study Group.   N Engl J Med.   2009 Apr 2;360(14):1395-407

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No Comments Posted in Hemodialysis
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