Archive for the ‘Pediatric Nephrology’ Category

September 18, 2012

Consensus Guidelines for the Prevention and Treatment of Catheter-related Infections and Peritonitis in Pediatric Patients Receiving Peritoneal Dialysis: 2012 Update

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This clinical guideline focuses on the prevention and treatment of catheter-related infections in pediatric patients on peritoneal dialysis.

1 Comment Posted in Clinical Practice Guidelines, Pediatric Nephrology, Peritoneal Dialysis
November 12, 2011

Late Breaking Clinical Trials at ASN 2011 – FISH study and more

The late breaking clinical trials session from the 2011 American Society of Nephrology meeting was held on November 12, 2011.  The following are summaries of some of the clinical trial results.  Access to the full details of these studies awaits publication in peer reviewed journals. Charmaine E. Lok et al.  The Fish Oil Inhibition of Stenosis […]

Comments Off on Late Breaking Clinical Trials at ASN 2011 – FISH study and more Posted in Bone Mineral Metabolism, Clinical Trial Results, General Nephrology, Glomerulonephritis, Pediatric Nephrology, Renal Transplantation, Vascular Access
May 1, 2010

Interventions for bone disease in children with chronic kidney disease.

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This systematic review of interventions for bone disease in children with CKD concludes that all examined vitamin D formulations reduce PTH levels and that sevelamer as compared to calcium-based binders reduced serum calcium and hypercalcemic events. However, no reduction in hard clinical endpoints was identified.

Comments Off on Interventions for bone disease in children with chronic kidney disease. Posted in Bone Mineral Metabolism, Chronic Kidney Disease, Pediatric Nephrology
March 25, 2010

A Randomized Trial to Assess the Impact of Early Steroid Withdrawal on Growth in Pediatric Renal Transplantation: The TWIST Study

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Steroid withdrawal is attractive in pediatric transplantation due the adverse effect of steroids on linear growth. In this multi-centre randomized controlled trial, early steroid withdrawal in a daclizumab, tacrolimus and MMF regimen resulted in better growth than tacrolimus, MMF and conventional steroids. The rate of acute rejection was similar, although there were more infections in […]

Comments Off on A Randomized Trial to Assess the Impact of Early Steroid Withdrawal on Growth in Pediatric Renal Transplantation: The TWIST Study Posted in Pediatric Nephrology, Renal Transplantation
February 12, 2010

Pediatrics: Blood pressure target for renoprotection in children

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This review summarizes results of the landmark ESCAPE trial, which has shown that lowering the blood pressure target to below the 50th percentile slows pediatric chronic kidney disease progression.

Comments Off on Pediatrics: Blood pressure target for renoprotection in children Posted in Chronic Kidney Disease, Hypertension, Pediatric Nephrology
November 22, 2009

Strict Blood-Pressure Control and Progression of Renal Failure in Children

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This randomized controlled trial confirms the long-term renoprotective effect of intensified blood-pressure control among children treated with high dose angiotensin-converting-enzyme (ACE) inhibitor.

Comments Off on Strict Blood-Pressure Control and Progression of Renal Failure in Children Posted in Hypertension, Pediatric Nephrology
November 22, 2009

Immunosuppressant Therapy Adherence and Graft Failure Among Pediatric Renal Transplant Recipients

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Pediatric patients are a high-risk group for medication nonadherence post-transplant. This retrospective study used US Medicare prescription claims for immunosuppressive medications to assess the degree of non-adherence, and showed longer graft survival in adherent patients.

Comments Off on Immunosuppressant Therapy Adherence and Graft Failure Among Pediatric Renal Transplant Recipients Posted in Pediatric Nephrology, Renal Transplantation
March 25, 2009

KDOQI Clinical Practice Guideline for Nutrition in Children with CKD: 2008 update.

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Authoritative guidelines by KDOQI.

Comments Off on KDOQI Clinical Practice Guideline for Nutrition in Children with CKD: 2008 update. Posted in Clinical Practice Guidelines, Pediatric Nephrology