Archive for the ‘Renal Artery Stenosis’ Category

December 21, 2013

Stenting and Medical Therapy for Atherosclerotic Renal-Artery Stenosis

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The CORAL trial failed to show any benefit of renal-artery stenting when added on to medical therapy in patients with atherosclerotic renal-artery stenosis.

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August 20, 2010

Is There Any Reason to Stent Atherosclerotic Renal Artery Stenosis?

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This is commentary on the ASTRAL study (Revascularization versus medical therapy for renal artery stenosis. N Engl J Med. 2009;361(20):1953-1962.) discusses trial findings, limitations and implications for practice.

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August 20, 2010

Indications for renal revascularization—the landscape after the ASTRAL study

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This review discusses the implications of the STAR and ASTRAL studies on management of atherosclerotic renovascular disease and highlight an important study in progress, CORAL.   The authors summarize that “until completion of the CORAL study, it is prudent to restrict the endovascular intervention to only patients with tight RAS of the single functioning kidney or […]

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November 22, 2009

Revascularization versus Medical Therapy for Renal-Artery Stenosis

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This randomized, non-blinded study of patients with renovascular disease compared renal artery revascularization plus medical therapy vs medical therapy alone.  Those in the revascularization arm experience an increased rate of serious complications with no reduction in pre-defined clinical endpoints.

1 Comment Posted in Renal Artery Stenosis, Vascular Disease/Calcification
May 2, 2009

Stent Placement in Patients With Atherosclerotic Renal Artery Stenosis and Impaired Renal Function: A Randomized Trial.

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140 patients were randomized to determine the efficacy and safety of stent placement in patients with atherosclerotic renal artery stenosis and impaired renal function. The study concluded that stent placement with medical treatment had no clear effect on progression of renal dysfunction and, therefore, favored a conservative approach with cardiovascular risk factor management without stenting.

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