Chronic kidney disease is associated with incident cognitive impairment in the elderly: the INVADE study
This study aimed to assess the relationship between renal impairment and cognitive decline. Of the 3769 patients, 396 (10%) had cognitive impairment at the outset. After the 2-year follow-up, 194 participants (6.2%) developed new cognitive impairment. Multiple logistic regression analysis showed that moderate-to-severe impaired renal function was associated with incident cognitive impairment after 2 years in a large cohort of elderly subjects.