May 1, 2017

Cigarette smoking and chronic kidney disease in the general population: a systematic review and meta-analysis of prospective cohort studies 

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This meta-analysis looked at 15 prospective cohort studies, including 65 064 incident CKD cases.  Compared with never-smokers, the summary relative risks of incident CKD were 1.27 (95% CI 1.19–1.35) for ever-smokers, 1.34 (95% CI 1.23–1.47) for current smokers and 1.15 (95% CI 1.08–1.23) for former smokers. The SRRs for end-stage renal disease development were 1.51 (95% CI 1.24–1.84) for ever-smokers, 1.44 (95% CI 1.00–2.09) for former smokers and 1.91 (95% CI 1.39–2.64) for current smokers.  This data suggests that cigarette smoking is an independent risk factor for incident CKD.

 

 

 

 

 

 

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Chronic Kidney Disease, Clinical Nephrology