September 21, 2015

Corticosteroids in IgA Nephropathy: A Retrospective Analysis from the VALIGA Study

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This retrospective study assessed 1147 patients with IgA nephropathy from the European Validation Study of the Oxford Classification of IgAN (VALIGA) cohort.  From this group as well a propensity matched cohort, the authors concluded that corticosteroids reduced proteinuria and the rate of renal function decline and increased renal survival even in patients with an eGFR < 50 ml/min compared to renin angiotensin system blockade alone.  Furthermore, the benefits were proportionate to the level of proteinuria.

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