January 28, 2012

Dialysate Sodium Concentration and the Association with Interdialytic Weight Gain, Hospitalization, and Mortality

Hecking M, Karaboyas A, Saran R, Sen A, Inaba M, Rayner H, Hörl WH, Pisoni RL, Robinson BM, Sunder-Plassmann G, Port FK.   Clin J Am Soc Nephrol.   2012 Jan;7(1):92-100

This analysis of observational DOPPS data examined the impact of reduced dialysate sodium on clinical outcomes.  While lowering dialysate sodium was associated with lower interdialytic weight gain, it was also associated with increased hospitalization.  No mortality benefit was associated with reduced dialysate sodium.

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