January 24, 2015

Effect of Low Versus High Dialysate Sodium Concentration on Blood Pressure and Endothelial-Derived Vasoregulators During Hemodialysis: A Randomized Crossover Study.

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This interesting study looked at the effect of dialysate sodium concentrations (low (5 mEq/L below serum sodium) versus high (5 mEq/L above serum sodium)) and the effect on blood pressure during dialysis.  The results showed that low sodium dialysate significantly decreased systolic BP and ameliorated intradialytic hypertension. However, longer studies are needed to determine the long-term effects.

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Clinical Nephrology, Fluid & Electrolytes, Hemodialysis