September 21, 2015

Effect of Neutral-pH, Low–Glucose Degradation Product Peritoneal Dialysis Solutions on Residual Renal Function, Urine Volume, and Ultrafiltration: A Systematic Review and Meta-Analysis

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This meta-analysis of eleven trials of 643 patients used a random effects model to evaluate the effect of peritoneal dialysate with neutral-pH, low-glucose degradation products on residual renalfunction, urine volume, peritoneal ultrafiltration, and peritoneal small-solute transport (dialysate to plasma creatinine ratio).  The results show a positive effect on preservation of residual renal function and greater urine volumes only.  However, the authors rightly conclude more studies are needed to determine the effect of these more costly solutions on harder clinical outcomes.

Related Articles:

Clinical Nephrology, Peritoneal Dialysis, Residual Renal Function

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