July 13, 2015

Effect of Remote Ischemic Preconditioning on Kidney Injury Among High-Risk Patients Undergoing Cardiac Surgery A Randomized Clinical Trial

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This very interesting multicentre Cleveland Clinic study looked at remote ischemic preconditioning (3 cycles of 5-minute ischemia and 5-minute reperfusion in one upper arm after induction of anesthesia) or sham remote ischemic preconditioning (control), both via blood pressure cuff inflation in high-risk patients undergoing cardiac surgery.  These results show that ischemic preconditioning significantly reduced both the rate of acute kidney injury and the need for renal replacement.

Related Articles:

Acute Kidney Injury, Clinical Nephrology, Clinical Trial Results

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