June 14, 2011

Elevated Fibroblast Growth Factor 23 is a Risk Factor for Kidney Transplant Loss and Mortality

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Fibroblast growth factor 23 (FGF 23) is a protein that is elevated in CKD and ESRD and is associated with increased risk of cardiovascular disease and death. In this single-center study, higher FGF 23 levels in a group of stable renal transplant patients were associated with a greater risk of mortality and graft failure. Whether interventions to lower FGF 23 levels would reduce mortality and graft loss is unknown.

Full text kindly provided by the American Society of Nephrology.

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