July 8, 2012

Estimating Glomerular Filtration Rate from Serum Creatinine and Cystatin C

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This study evaluated three equations for estimating glomerular filtration rate using creatinine alone, cystatin C alone or both. The mean GFR was 68 ml/min in the development set and 70 ml/min in the validation set. In the validation set, the creatinine-cystatin C equation performed better than equations using either marker alone. However, the routine use of this equation is limited by the availability of cystatin C assays.

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