April 19, 2014

High versus Low Blood-Pressure Target in Patients with Septic Shock

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This multicentre, open label trial randomized over 700 patients with septic shock to undergo resuscitation to MAP target of 80-85 mmHg or 65-70 mmHg. The primary outcome of mortality was no different in either group at 28 or 90 days. However, the higher target group required less renal replacement therapy.

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Acute Kidney Injury, Clinical Nephrology, Clinical Trial Results, General Nephrology

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