This randomized controlled trial compared the use of hydroxyethyl starch (HES) versus saline for fluid resuscitation. While there was no significant difference in 90-day mortality, patients who received resuscitation with HES were more likely to have renal injuryand be treated with renal-replacement therapy.
- High versus Low Blood-Pressure Target in Patients with Septic Shock
- Intensity of Continuous Renal-Replacement Therapy in Critically Ill Patients
- Association of hydroxyethyl starch administration with mortality and acute kidney injury in critically ill patients requiring volume resuscitation: a systematic review and meta-analysis.