June 6, 2010

Increased Incidence of Angioedema with ACE Inhibitors in Combination with mTOR Inhibitors in Kidney Transplant Recipients

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In this single center, retrospective cohort study, a higher incidence of angioedema was seen in transplant patients being treated with sirolimus as opposed to those treated with alternative immunosuppressive regimens. This has been previously reported in other case series of renal transplant patients, as well as other groups of patients treated with sirolimus (e.g. non-renal transplant patients).

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