December 14, 2009

Interleukin-2 Receptor Antibody Reduces Rejection Rates and Graft Loss in Live-Donor Kidney Transplant Recipients

Lim WH, Chang SH, Chadban SJ, Campbell SB, Dent H, Russ GR, McDonald SP.   Transplantation.   2009 Nov 27;88(10):1208-13

This registry analysis found that compared to no antibody therapy, living-donor recipients who received IL-2 receptor antibody treatment at the
time of transplant were at lower risk for acute rejection. At 5 years, IL-2 receptor antibody was also associated with a lower risk of overall graft failure at 5 years, and better renal function at 1 year, although not at 3 years.

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Renal Transplantation

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