August 5, 2011

Moderate dietary sodium restriction added to angiotensin converting enzyme inhibition compared with dual blockade in lowering proteinuria and blood pressure: randomised controlled trial

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This small randomized trial including patients with non-diabetic nephropathy looked at the addition of dietary sodium restriction or angiotensin receptor blockade (or their combination), in patients receiving background treatment with angiotensin converting enzyme (ACE) inhibition at maximum dose. Dietary sodium restriction to a level recommended in guidelines was more effective than dual blockade for reduction of proteinuria and blood pressure. Hard clinical endpoints were not examined in this study.

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