Mycophenolate mofetil versus cyclophosphamide for induction treatment of lupus nephritis.
Appel GB, Contreras G, Dooley MA, Ginzler EM, Isenberg D, Jayne D, Li LS, Mysler E, Sánchez-Guerrero J, Solomons N, Wofsy D, Aspreva Lupus Management Study Group. J Am Soc Nephrol. 2009 May;20(5):1103-12
This study randomized 370 patients with class III to V lupus nephritis to MMF or intravenous cyclophosphamide during a 24-week induction period. Both groups received a tapering dose of prednisone. No difference in response rate was detected between groups.
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