April 19, 2014

Non-selective β Blockers Increase Risk for Hepatorenal Syndrome and Death in Patients with Cirrhosis and Spontaneous Bacterial Peritonitis

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This interesting study of non-selective beta blockers in patients with cirrhosis and spontaneous bacterial peritonitis shows that their use increases the risk of acute kidney injury and hepatorenal syndrome in this population. The authors advise against their use in these patients. Furthermore, they worsen hemodynamic instability as well as increase length of hospitalization.

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