October 8, 2011

Persistent Asymptomatic Isolated Microscopic Hematuria in Israeli Adolescents and Young Adults and Risk for End-Stage Renal Disease

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This study linked an ESRD registry to retrospective medical data for persons aged 16-25 examined for military fitness.  It showed that persistent asymptomatic microscopic hematuria was associated with an increased risk of ESRD, with an adjusted hazard ratio of 18.5 [95% CI, 12.4-27.6].  While the absolute risk of ESRD in patients with microscopic hematuria remains low, the results of this paper are a warning against complacency and reinforce the need for longitidunal follow up of such patients.

See associated editorial:
Has the Time Come to Include Urine Dipstick Testing in Screening Asymptomatic Young Adults?
http://jama.ama-assn.org/cgi/content/full/306/7/764

Related Articles:

Chronic Kidney Disease, Glomerulonephritis

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