Randomized Controlled Trial Comparing Mupirocin and Polysporin Triple Ointments in Peritoneal Dialysis Patients: The MP3 Study
This double-blind multicentre RCT studied the effectiveness of topical Polysporin Triple ointment as compared to mupirocin to peritoneal dialysis catheter exit sites. Twice the number of patients experienced redness at the exit site in the Polysporin Triple group (14 versus 6, P=0.10) with a higher rate of fungal exit site infection (0.07 versus 0.01; P=0.02) and peritonitis (0.04 versus 0.00, respectively; P<0.05). The authors suggest that Polysporin Triple should not be used for prophylaxis of PD-related infections.
- Fungal Peritonitis in Peritoneal Dialysis Patients: Successful Prophylaxis with Fluconazole, as Demonstrated by Prospective Randomized Control Trial
- Early Catheter Removal Improves Patient Survival In Peritoneal Dialysis Patients with Fungal Peritonitis: Results of a Ninety-Four Episodes of Fungal Peritonitis at a Single Center
- PD Access Guide