November 10, 2015

Randomized Trial on Efficacy of Mycophenolate Mofeti versus Tacrolimus in Maintaining Remission in Children with Steroid Resistant Nephrotic Syndrome

These are results as presented at the 2015 American Society of Nephrology Kidney Week.

In children with steroid resistant nephrotic syndrome who were successfully put into remission, maintenance therapy with MMF 750-1000 mg/m2was compared to tacrolimus 0.1-0.15 mg/kg/day. The primary endpoint of preserved complete or partial remission was achieved in 90.3% of the tacrolimus arm vs 44.8% of the MMF arm, p = 0.00045.

Full results publication of these findings is eagerly awaited.

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