This randomized controlled trial compared two strategies of blood pressure management after spontaneous intracerebral hemorrhage. Patients were randomized intensive blood treatment to target a systolic BP of
No difference was seen in the composite of death or major disability. However, a significantly lower modified Rankin scores was seen with intensive treatment (odds ratio for greater disability, 0.87; 95% CI, 0.77 to 1.00; P=0.04).
- Intensive vs Standard Blood Pressure Control and Cardiovascular Disease Outcomes in Adults Aged ≥75Years: A Randomized Clinical Trial
- Effects of intensive blood pressure lowering on cardiovascular and renal outcomes: updated systematic review and meta-analysis.
- A Randomized Trial of Intensive versus Standard Blood-Pressure Control