November 29, 2011

Risk of Pneumocystis jiroveci pneumonia in patients long after renal transplantation

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Pneumocystis jiroveci pneumonia is a well-recognized complication after transplantation, and current guidelines recommend prophylaxis for three-six months post-transplant. In this study, nine patients who develop Pneumocystis pneumonia a median of 19 months post-transplant were compared to a group of control patients. Cases had significantly lower lymphocyte counts than controls, as well as lower CD4 counts, and a higher number of other infectious episodes. Review of lymphocytes counts after the early post-transplant period may identify patients at an increased risk of Pneumocystis and other infectious complications.

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