July 10, 2009

Rituximab and mycophenolate mofetil for relapsing proliferative lupus nephritis: a long-term prospective study

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This prospective, observational study looked 10 women with subnephrotic proliferative lupus nephritis who relapsed on maintenance MMF or Imuran. They were treated with 4 weekly infusions of rituximab combined with MMF and prednisolone. This combination was found to have low toxicity and 7 patients were found to have a complete remission. This seems to warrant further study in a randomized controlled trial.

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  • hariharan v

    am interested in knowing further of the long term efficacy of single course of rituximab. tks.