January 28, 2012

Sodium Intake, ACE Inhibition, and Progression to ESRD

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The impact of sodium intake on clinical outcomes has recently come under some scrutiny and the topic is surrounded by debate.  In this retrospective analysis of the REIN study, patients with non-diabetic CKD who had high dietary salt (>14 g daily) had a blunted antiproteinuric effect from ACE inhibitor therapy and increase the risk for ESRD, independent of BP control.

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