November 25, 2012

Ultrafiltration in Decompensated Heart Failure with Cardiorenal Syndrome

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This randomized controlled trial compared ultrafiltration versus stepped pharmacologic therapy in patients with acute decompensated heart failure and a decline in kidney function (cardiorenal syndrome). Ultrafiltration was found to be inferior in achieving the bivariate endpoint in change in serum creatinine and body weight after 96 hours. The ultrafiltration group experienced a higher rate of serious adverse events (72% vs 57%, p=0.03).

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Acute Kidney Injury, Cardiorenal Syndrome, Critical Care

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