December 22, 2011

Urinary Sodium and Potassium Excretion and Risk of Cardiovascular Events

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An observational analysis of cohorts from the ONTARGET and TRANSCEND trials looked at the association of urinary sodium and potassium with CV events and mortality. Sodium excretion and CV events showed a J-shaped relationship: sodium excretion of  < 3 g and >7 g per day was associated with an increased risk of CV events.  Risk of stroke was less likely with higher potassium excretion.
Accompanying Editorial “Urinary Sodium and Cardiovascular Disease Risk: Informing Guidelines for Sodium Consumption”
http://jama.ama-assn.org/content/306/20/2262.extract

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