October 1, 2008

Vitamin D in chronic kidney disease: is the jury in?

de Boer IH, Kestenbaum B.   Kidney Int.   2008 Oct;74(8):985-7

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Abstract:

Vitamin D shows promise for improving diverse health outcomes among patients with chronic kidney disease. Observational studies of vitamin D medications have contributed important evidence for broad beneficial clinical effects of vitamin D beyond actions on bone. However, such studies are limited by the potential for confounding by indication. A large randomized controlled trial is now needed to test the hypothesis that vitamin D therapy improves clinical outcomes in patients with kidney disease.

Bone Mineral Metabolism