May 1, 2010

Vitamins C and E to Prevent Complications of Pregnancy-Associated Hypertension

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This multicenter, randomized, double-blind trial randomized low risk nulliparous women to daily supplementation with vitamin C and vitamin E or placebo early in pregnancy. The study failed to reduce the primary outcome of severe pregnancy-associated hypertension alone or severe/mild hypertension with elevated liver-enzyme levels, thrombocytopenia, elevated serum creatinine levels, eclamptic seizure, medically indicated preterm birth, fetal-growth restriction, or perinatal death.

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